How acne affects a healthy immune system
A common form of acne called acne vulgaris is caused by a group of bacteria called Candida albicans, and it can cause serious side effects.
But researchers have been working to understand what triggers it.
The team has now found a way to treat it.
A new study by a team of researchers from the University of North Carolina at Chapel Hill shows that it is possible to treat acne by combining a diet rich in probiotics and an anti-inflammatory drug.
They report their results in the journal, The Lancet.
The researchers found that the probiotic, Lactobacillus casei, and the anti-inflammation drug, metformin, were effective in reducing inflammation and acne.
The study involved 30 healthy adults, and was funded by the National Institutes of Health (NIH).
They fed the participants the combination of probiotics, probiotics with a Bifidobacterium longum strain and a drug known as erythromycin, for about a month.
After three months, all the participants were asked to undergo a skin biopsy.
The participants were randomly assigned to receive either the probiotics or the anti-(Bifidofacillus)-probiotic group.
They then went on a four-month diet that consisted of a standard American diet, and their skin biopsies were taken.
The probiotics included Lacto-Bacteroides lactis, L. bulgaricus, L., Bifidoides vulgare, B. vulgari, B., B. casei and B. lactis.
The anti-acne drug, erythrocyte cyclase inhibitors, or ECTs, included the antibiotics fluticasone propionate, dacron sulfate, triclosan and oxacillin-clavulanate.
The anti-acid drug, fluticase inhibition, was used to treat inflammation in the skin.
The anti inflammatory drug, carboplatin, was added to the anti inflammatory treatment.
Both probiotics were well tolerated.
In the probotics group, more than 90 percent of the participants experienced good or good clinical response.
The probiotics treated significantly less inflammation than the antiacne group.
In addition, participants who consumed the probionic diet reported less flare-ups of skin infection, and less skin irritation.
The team said that the results could help clinicians in treating patients with acne vulgarosum, a potentially serious autoimmune condition.
“These results suggest that probiotic-derived antiinflammatory medications can be useful in treating acne vulgarosa,” said study co-author Robert S. Lee, a professor of dermatology and of integrative medicine at the University at Albany.
“They may help reduce the severity of the acne vulgaroses, but also increase the quality of life and reduce the risk of complications.”